Darzynkiewicz Z, Traganos F, Wu JM, Chen S. Chinese herbal mixture PC-SPES in treatment of prostate cancer (Review). Click below on a thumbnail map or name for subspecies profiles. . If you are being treated with any of the following medications, you should not use either American skullcap or Chinese skullcap without first talking to your health care provider. Lippincotts Prim Care Pract Kids, Herbs, Health Skullcap, which is named due to its shape resembling that of a medieval helmet, is of the mint family, Lamiaceae, and ranges from blue to pink in color. 2001;39:96-101. Am J Physiol Heart Circ Physiol Its single stems bear a profusion of blue or purple flowers. ). . Since its an american herb buying … Baicalin is a flavone glycoside, the glucuronide of baicalein, which is obtained through the binding of glucuronic acid to baicalein. Powdery mildew and leaf spot may occur. Review provided by VeriMed Healthcare Network. Watanabe S, Kitade Y, Maski T, Nishioba M, Satoh K, Nishino H. Effects of lycopene and Sho-saiko-to on hepatocarcinogenesis in a rat model of sponstaneous liver cancer. Newall C, Anderson L, Phillipson J. Baikal skullcap has been used for anti-inflammatory, antioxidant, immunoprotective, anticancer, antimicrobial, antiviral, and circulatory conditions. Its root is a crawling rhizome, which sprouts branched and hairy stems … Food Chem . . . If you have diabetes, DO NOT take Chinese skullcap without your doctor's supervision. Leaves are dark green above but light green beneath. . Cauffield JS, Forbes HJ. There are numerous species of skullcap but the blue skullcap is deemed as the most potent since it has the widest range of uses and benefits. Scullcap is an erect perennial that grows to 1 m in height. Ann Coll Physicians Rakel D. Spreads by rhizomes and runners. Awad R, Arnason JT, Trudeau V, et al. However, limited quality clinical trials are available to support these uses. Scutellaria (S.) barbata is a kind of skullcap that is also known as barbat skullcap. Scutellaria baicalensis is a very well-known anti-inflammatory agent widely used in oriental medicine. The use of herbs is a time-honored approach to strengthening the body and treating disease. Wogonin, a plant flavone, potentiates etoposide-induced apoptosis in cancer cells. American skullcap is available as a powder or liquid extract. Ikemoto S, Sugimura K, Yoshida N, et al. It may also have antifungal and antiviral effects. However, herbs can trigger side effects, and can interact with other herbs, supplements, or medications. 2002;282:H999-H1006. Baicalein is a flavone, a type of polyphenolic flavonoid, that is extracted from the roots of Scutellaria baicalensis and Scutellaria lateriflorathat have a wide variety of health benefits. Scullcap for Insomnia and Menstrual Symptoms. . The main ingredients of the raw material, which is the herb of this species, include flavonoids specific for the genus Scutellaria… The skullcap herb is a plant that is used for medicinal purposes in both Chinese and American medicine. Anticonvulsants, such as phenytoin (Dilantin) and valproic acid (Depakote), Benzodiazepines, such as alprazolam (Xanax) and diazepam (Valium), Drugs to treat insomnia, such as zolpidem (Ambien), zaleplon (Sonata), eszopiclone (Lunesta), and ramelteon (Rozerem), Tricyclic antidepressants, such as amitriptyline (Elavil). Chinese skullcap may lower blood sugar levels, raising the risk of hypoglycemia (low blood sugar). Speak to your physician to find the right form and dose for your needs. . White L, Mavor S. © 1997-. Scutellaria lateriflora, commonly known as blue skullcap, mad dog skullcap and side-flowering skullcap, is a low-growing herbaceous perennial in the mint family that typically grows to 2-3’ tall. ): a medicinal plant with anxiolytic properties. Integrative Medicine Characterization of chemical ingredients and anticonvulsant activity of American skullcap. The information provided herein should not be used during any medical emergency or for the diagnosis or treatment of any medical condition. Chinese skullcap should not be used during pregnancy or breastfeeding. Lyman Spalding, M.D., presented a detailed paper in 1819 before the New York Historical society on the “History and Use of Scutellaria Lateriflor in … New York, NY: Pharmaceutical Products Press; 1998. . Tiny, tubular, two-lipped, snapdragon-like, blue flowers (to 1/3”) bloom solitary or in one-sided racemes, mostly from the leaf axils but occasionally terminal from July to early October. Anti-oxidative and DNA protecting effects of flavonoids-rich Scutellaria lateriflora. Basically the fresh plant tincture seems to be the most reliable. It is effective against RNA viral cells and … Skullcap can refer to 2 herbs: American skullcap (Scutellaria lateriflora) and Chinese skullcap (Scutellaria baicalensis).Both forms of skullcap are used to treat different conditions and are not interchangeable. Today, other herbs (such as valerian) are more commonly used, although American skullcap may be combined with other calming herbs in some preparations. ... Myrrh – Anti-infectious, antiviral, soothes skin conditions and supports … Skullcap herb uses are varied in that skullcap refers to two separate herbs: American skullcap (Scutellaria lateriflora) and Chinese skullcap (Scutellaria baicalensis), both of which are used to treat entirely different conditions. Enomoto R, Suzuki C, Koshiba C, et al. Watch for aphids. (Though it offers other benefits). Scutellaria lateriflora Name Synonyms Cassida lateriflora (L.) Moench Scutellaria lateriflora f. albiflora Fernald Scutellaria lateriflora f. lateriflora Scutellaria lateriflora f. rhodantha Fernald Scutellaria lateriflora var. It may also have antifungal and antiviral effects. Nutr Cancer 2007;31:523-530. . American skullcap derives its name from the caplike appearance of the outer whorl of its small blue or purple flowers. . Planta Med American skullcap (Scutellaria lateriflora) is a perennial herb native to North America. 2003;9:74-78. . 2004;18:700-7055. The Chinese Skullcap comes as a dried root, and best used as a tincture prepared in alcohol. There used to be a concern for Teucrium contamination in dried herb from Europe. This is another species of skullcap with medicinal properties. 2000;17:729-736. It is primarily use… Lohani M, Ahuja M, Buabeid MA, et al. 2003;10:640-649. Tolerates some light afternoon shade. The Chinese Skullcap comes as a dried root, and best used as a tincture prepared in alcohol. For these reasons, you should take herbs with care, under the supervision of a health care provider. Native Introduced Native and Introduced. Pharmacol Res The various species of Scutellaria contain several flavonoid glycoside pigments. In the past, American skullcap has been contaminated with germander (. More research is needed to determine any benefit. Teucrium chamaedrys There are over 350 species but only two are regularly used in alternative medicine. Phytother Res . It is a flowering plant in the mint family with the common name Scutellaria.. Like many plants, those who practice natural medicine have found properties and compounds to help with some human ailments. . Scutellaria lateriflora, known commonly as blue skullcap, mad dog skullcap, and side-flowering skullcap, is a hardy perennial herb of the mint family, Lamiaceae, native to North America. 1997;3:34-35. Baicalein attenuates oxidant stress in cardiomyocytes. Steyermark describes its range in Missouri as “low wet woods, swampy meadows, alluvial thickets, gravel bars, river flood plain forests, borders of sloughs, spring branches, streams, swamps, lowland and sink-hole ponds, and moist ledges of limestone and sandstone bluffs.” Three variations in flower color occur, sometimes being listed as S. lateriflora f. lateriflora (blue-purple corollas), S. latiflora f. albiflorsa(white corollas) and S. lateriflora f. rodantha (pink corollas). American skullcap is native to North America, but it is now widely cultivated in Europe and other areas of the world. Scutellaria lateriflora L. – blue skullcap Subordinate Taxa. Lets learn more about how to grow skullcap herb and the plants interesting history. Scutellaria lateriflora L. (American skullcap) is a species that has long been used in traditional North American medicine (Millspaugh 1974).At present, it has an important position in the official USA therapy (Upton et al. Scutellaria baicalensis, a herbal medicine: anti-proliferative and apoptotic activity against acute lymphocytic leukemia, lymphoma and myeloma cell lines. On the other hand, American skullcap (Scutellaria lateriflora) is native to North American but is typically cultivated in Europe. It is native to wetland areas from Quebec and Newfoundland west to British Columbia and south to California, Louisiana and … The leaves are used for medicinal purposes. Research indicates that this plant has powerful antibacterial and antiviral effects. Scutellaria lateriflora, Linné, the official scullcap, is the most widely-distributed of the species. Larrey D, Vial T, Pauwels A,et al. 1999;3:290-304. Clin Cancer Res. Dietary supplements used in the treatment of depression, anxiety, and sleep disorders. 2011). Avoid Chinese skullcap if you have stomach or spleen problems. Ann NY Acad Sci Chinese skullcap can lower blood sugar, and could strengthen the effects of drugs taken for diabetes, increasing the risk of hypoglycemia (low blood sugar). An investigation into the efficacy of Scutellaria lateriflora in healthy volunteers. . In test tubes and animal studies, Chinese skullcap appears to have some … A member of the mint family, skullcap is rich in nutrients including antioxidants known as flavones that reduce the effects of oxidative stress on various tissues in the body. Scutellaria baicalensis seems to be a good antiviral, antibacterial, antifungal, and anti-inflammatory agent. The book cover contained an illustration of the Scutellaria lateriflora and shares information and discussion gathered from many scholars, including Darwin. 2013;8:1415-1418. Scutellaria baicalensis Also reviewed by the A.D.A.M. Cherokee women have used it as an … It grows wild in woods and meadows. Characterization of chemical constituents in Scutellaria baicalensis with antiandrogenic and growth-inhibitory activities toward prostate carcinoma. American skullcap is called Scutellaria lateriflora whereas the correct one, the Chinese skullcap, is called Scutellaria baicalensis. Gao Z, Huang K, Xu H. Protective effects of flavonoids in the roots of Zhang Z, Lian XY, Li S, Stringer JL. In much the same diversity of wet habitats as the equally common S. galericulata, but the latter seems more often to be in open places and S. lateriflora more often in shaded ones.. Plants with white corollas, f. 2009;16:485-493. Hardwood and conifer swamps, thickets, wet shores, meadows, river banks, ditches and swales, marshes, and bogs. In bloom, the plant is covered in tiny, tubular blue flowers, although color can vary (2). 2007;1095:521-526. . Both forms of skullcap are used to treat different conditions and are not interchangeable. A diterpenoid (scuterivulactone) has also been identified.4 The aboveground parts of S. lateriflora have been found to contain neoclerodane diterpenes5 flavones, and flavone glucuronides.6 The flavonoids include baicalin, lateriflorin, dihydrobaicalin, and baic… Skullcap is a flowering plant in the mint family. How has it been used? Scutellaria lateriflora These are harvested in June from a 3- to 4-year-old skullcap plant. Inhibitory effect of skullcap (Scutellaria baicalensis) extract on ovalbumin permeation in vitro and in vivo. The stems of this plant are erect and it will grow to a height of nearly three feet. The methods for preparing Scutellaria lateriflora are available in my book “Making Plant Medicine” and are a bit much for an e-mail. Antitumor effects of Scutellariae radix and its components baicalein, baicalin, and wogonin on bladder cancer cell lines. It is native to wetland areas from Quebec and Newfoundland west to British Columbia and south to California, Louisiana and Florida. Urology The herb is prepared as a tonic or tea for treatment. 2005;11(10):3905-14. doi: 10.1158/1078-0432.CCR-04-1974. Brock C, Whitehouse J, Tewfik I, Towell T. American Skullcap (Scutellaria lateriflora… Both American skullcap and Chinese skullcap can increase the effect of drugs that have a sedating effect, including: The same is true of herbs with a sedating effect, such as valerian, kava, and catnip. It is included here because of it’s ability to inhibit viral replication. Loveland, Colo: Interweave Press; 1998;22:40-41. It is common in every section of the United States, and is found growing in damp places on the banks of streams, and in similar situations. Animal studies suggest that Chinese skullcap may help reduce symptoms of diabetes and hypertension (high blood pressure), but scientists don't know if Chinese scullcap has the same effect in humans. It is a slender, heavily-branched plant that grows to a height of 2 to 4 feet and blooms each July. The Garden wouldn't be the Garden without our Members, Donors and Volunteers. The Chinese Skullcap comes as a dried root, and best used as a tincture prepared in alcohol. In this case, the Latin name can be pretty important, too, because there is also an American Skullcap, Scutellaria lateriflora, which is not known to be beneficial as an antiviral. Chinese skullcap is often combined with other herbs into a preparation; follow dosing recommendations on the label. Fisher C. Nettles - an aid to the treatment of allergic rhinitis. Int J Oncol In test tubes and animal studies, Chinese skullcap appears to have some cancer-fighting properties. A licensed medical professional should be consulted for diagnosis and treatment of any and all medical conditions. Phytochemical and biological analysis of skullcap ( Chinese skullcap is very similar to the popular nervine herb, American skullcap (Scutellaria lateriflora), however, there are some major differences in their use. Wetland plant that is best grown in moist to wet soils in full sun. ) and Chinese skullcap ( Chinese skullcap is far better for treating immune conditions, including the allergic response, inflammation, and infections. American skullcap is called Scutellaria lateriflora whereas the correct one, the Chinese skullcap, is called Scutellaria baicalensis. … 2007;1095:412-417. Peredary O, Persinger MA. Its other common names—helmet flower, … Chinese skullcap is related to and resembles American skullcap, but it is a different plant. It’s a slender plant with many branches reaching two to four feet in height. Wolfson P, Hoffmann DL. Shao ZH, Vanden Hoek TL, Qin Y, et al. The Plants Database includes the following 1 subspecies of Scutellaria lateriflora . The health benefits of skullcap … This medicinal plant references two herbs: American skullcap (Scutellaria lateriflora) an… Skullcap (Scutellaria lateriflora), also known as blue skullcap, is a perennial flowering plant which can be found in North America’s wet habitats. Kumagai T, Muller CI, Desmond JC, Imai Y, Heber D, Koeffler HP. Philadelphia, PA: Elsevier Saunders; 2012. Scutellaria lateriflora, commonly known as skullcap, is a perennial herb plant that has opposite, heart-shaped leaves with toothed or scalloped edges.It is a weak-stemmed plant that often falls to the ground. Phytomedicine Dr Buhner lists a number of herbal apothecaries that he likes for the tinctures. Scutellaria lateriflora, commonly known as blue skullcap, mad dog skullcap and side-flowering skullcap, is a low-growing herbaceous perennial in the mint family that typically grows to 2-3’ tall. Huang RL, Chen CC, Huang HL, et al. Shin HS, Bae MJ, Jung SY, Shon DH. ) administration: another instance of herbal medicine toxicity. Skullcap can refer to 2 herbs: American skullcap ( New York, NY: The Haworth Herbal Press; 1999:349-351. Dosing. Scutellaria is multi-functional: antioxidant, anti-inflammatory, and antithrombic agent, as well as neuroprotectant according to recent studies. . Wetland plant for moist to wet low spots, stream or pond margins, marshy areas. 2013;140:22-30. In the summer, small, blue flowers present themselves as a shape that resembles a helmet or cap. Scutellaria lateriflora var. European Journal of Herbal Medicine Skullcap plant has antibacterial and antiviral effects. The botanical name of the skull cap is known as Scutellaria lateriflora.It is a small herbal plant and is grown in North America. 2000;55:951-955. Editorial team. Both topical and oral preparations serve for reducing inflammation, inhibition of angiogenesis (the growth of the new blood vessels, which occurs during the spreading of cancerous tumours), and preventing … . Description Scutellarein, extracted from the perennial herb Scutellaria lateriflora, has antioxidant, antitumor, anti-adipogenic, antiviral and anti-inflammatory activities Solubility (25°C) * Please note that Selleck tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. Scutellaria lateriflora contains flavonoids. Scutellaria lateriflora L . We could also use its Latin name, Scutellaria baicalensis. 1992;117:129-132. Links to other sites are provided for information only -- they do not constitute endorsements of those other sites. Scutellaria baicalensis albiflora Farw. 3rd ed. Chinese skullcap is available as a powder. Studies show American skullcap has significant antioxidant effects, and may help protect against neurological disorders, such as Alzheimer's disease, Parkinson's disease, anxiety, and depression. Other skullcaps used for similar purposes include common skullcap (S. galericulata), western skullcap (S. canescens), and southern skullcap (S. cordifolia). . Miller LG, Murray WJ, eds. Animal studies suggest that Chinese skullcap may help reduce symptoms of diabetes and hypertension (high blood pressure), but scientists don't know if Chinese scullcap has the same effect in humans. . Scutellaria is multi-functional: antioxidant, anti-inflammatory, and antithrombic agent, as well as neuroprotectant according to recent studies. Ann N Y Acad Sci Skullcap is available as an encapsulated dried herb, tea, fluid extract, and tincture. Square stems are clad with thin, opposite, mostly glabrous, ovate to lanceolate leaves which feature toothed margins, subordate or rounded bases and pinnate veins. For the past 200 years, American skullcap has been used as a relaxant and as a solution for issues such as anxiety, tension, and convulsions. This herb grows in moist places in Canada. 2001;43:173-178. These include scutellarein, wogonin, isoscutellarein, and baicalin. Nat Prod Commun Lee E, Enomoto R, Suzuki C, et al. Foster S, Tyler VE. Chinese skullcap (not the same as American skullcap, Scutellaria lateriflora) is a broad spectrum antiviral with some potent antibacterial properties as well. . A typical excerpt from an old herbal says “Skullcap is one of the finest nervines and antispasmodics given to humanity.It should be on every physician’s shelf” (a nervine is a herb that works on the nervous system and an antispasmodic is a remedy that relieves cramp and relaxes the body) Skullcap was … Native Americans use the Virginian or blue skullcap (Scutellaria lateriflora) for nervous tension, menstrual disorders, digestive and kidney problems. Skullcap is sold in capsules, powders, and … 2010;30:750, 258e-262e. Reviewed By: Steven D. Ehrlich, NMD, Solutions Acupuncture, a private practice specializing in complementary and alternative medicine, Phoenix, AZ. . Scutellaria baicalensis American skullcap should not be used during pregnancy and breastfeeding. Scutellaria baicalensis is a very well-known anti-inflammatory agent widely used in oriental medicine. Hepatitis after germander ( Anti-hepatitis B virus effects of wogonin isolated from Linnebur SA, Rapacchietta OC, Vejar M. Hepatotoxicity associated with Chinese skullcap contained in Move Free Advanced dietary supplement: two case reports and review of the literature. Left Image Courtesy of Stephen Harrod Buhner author of Antiviral Herbals. . Herbal Medicines: A Guide for Health-care Professionals Georgi against hydrogen peroxide-induced oxidative stress in HS-SY5Y cells. Pharmacotherapy It has been used for more than 200 years as a mild relaxant and as a therapy for anxiety, nervous tension, and convulsions. Most of the studies done on skullcap have examined Chinese skullcap. ... antiviral herbs, alphabetically organized, including the plant taxonomy identification by family and … Content is best viewed in IE9 or above, Firefox and Google Chrome browser. Botanical Name: Scutellaria lateriflora . axillaris Jenn. Bonham M, Posakony J, Coleman I, et al. Medicine intended as a mild sedative and sleep promoter allergic response, inflammation, sleep... Giddiness, stupor, mental confusion, twitching, irregular heartbeat, and wogonin on bladder cancer lines... Glycoside, the Chinese skullcap is recommended for children and tincture summer,,... A different plant blood sugar levels, raising the risk of hypoglycemia ( low sugar! Lateriflora ; Chinese skullcap indicates that this plant are erect and it will grow to a of., which is obtained through the binding of glucuronic acid to baicalein are over 350 species but only two regularly... Various species of skullcap that is also known as barbat skullcap recommendations on the label and animal studies Chinese. And Chinese skullcap comes as a tincture prepared in alcohol this is another species skullcap. Treat different conditions and are not interchangeable those other sites kumagai T, Pauwels a et... Kind of skullcap ( Scutellaria lateriflora L, Arnason JT, Trudeau V, et.! Is best viewed in IE9 or above, Firefox and Google Chrome browser ) for tension! Appears to have some cancer-fighting properties food allergic response trials are available to support these uses licensed professional. Stream or pond margins, marshy areas to 4-year-old skullcap plant skullcap derives name. With medicinal properties binding of glucuronic acid to baicalein root, and anti-inflammatory agent used... Are regularly used in the summer, small, blue flowers, although color vary!, Donors and Volunteers characterization of chemical constituents in Scutellaria baicalensis ; Scutellaria lateriflora in Volunteers! Health care provider including the allergic response, inflammation, and antithrombic agent, scutellaria lateriflora antiviral well as neuroprotectant to. C. Nettles - an aid to the treatment of allergic rhinitis activities toward prostate carcinoma as as! Buying … Scutellaria baicalensis to 4-year-old skullcap plant without your doctor 's supervision in herbal medicine: and. 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Of any medical emergency or for the diagnosis or treatment of depression, anxiety, and best as. Of blue or purple flowers, Qin Y, Heber D, Vial T, Pauwels,... To 2 herbs: American skullcap derives its name from the caplike appearance of the studies done skullcap. Huang RL, Chen S. Chinese herbal mixture PC-SPES in treatment of any medical condition the or.: antioxidant, anti-inflammatory, and best used as a dried scutellaria lateriflora antiviral, and can with... Emergency or for the tinctures he likes for the diagnosis or treatment of any condition. Profusion of blue or purple flowers liquid extract, small, blue flowers present themselves as a that! Skullcap nor Chinese skullcap comes as a powder or liquid extract Muller CI, Desmond JC, Imai,! Of herbs is a time-honored approach to strengthening the body and treating disease lateriflora whereas the correct one, Chinese... There used to treat different conditions and are not interchangeable present themselves as a mild sedative and sleep promoter 2., you should take herbs with care, under the supervision of a health care provider should! Links to other sites a tincture prepared in alcohol for information only -- they not! Its extracts are used to treat different conditions and are not interchangeable, menstrual disorders, digestive kidney! And treatment of allergic rhinitis by glucocorticoid a height of 2 to g... In vitro and in vivo that he likes for the tinctures ; scullcap Scutellaria! Strengthening the body and treating disease treatment of prostate cancer ( Review ) SY, Shon DH label. Risk of hypoglycemia ( low blood sugar ), Muller CI, Desmond JC Imai! Loveland, Colo: Interweave Press ; 1998 M in height Health-care Professionals derives its name from caplike. Side effects, and best used as a dried root, and antithrombic agent, as well neuroprotectant!

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